Chronic fatigue syndrome (ME/CFS) is a complex long-term condition characterised by profound fatigue lasting more than six months, not relieved by rest, along with cognitive difficulties, unrefreshing sleep and post-exertional worsening of symptoms.

Ordinary tiredness improves with rest and sleep. CFS fatigue is severe, lasts months, is not relieved by rest, worsens after activity (post-exertional malaise) and significantly limits daily function.

The exact cause is unknown. It often follows viral infections, and may involve immune, neurological and hormonal dysfunction. It is a real medical condition, not psychological.

There is no single test. Diagnosis is clinical, based on characteristic symptoms, after excluding other causes of fatigue such as anemia, hypothyroidism, sleep apnea, diabetes, depression and chronic infections.

Evaluation typically includes complete blood count, iron studies, thyroid function, blood sugar, vitamin B12 and D, liver and kidney function, ESR, CRP, and sometimes sleep studies or autoimmune panels.

There is no definitive cure, but many patients improve significantly with a structured management plan focused on pacing, sleep, graded activity and symptom control.

Post-exertional malaise (PEM) is a hallmark of CFS — symptoms worsen significantly after physical, mental or emotional exertion, often 12–48 hours later, and may last days.

Coverage depends on your policy. Hospitalisation for fatigue evaluation is usually covered. Contact the hospital desk to confirm details.